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Targeting human SET1/MLL family of proteins

The SET1 family of proteins, and in particular MLL1, are essential regulators of transcription and key mediators of normal development and disease. Here, we summarize the detailed characterization of the methyltransferase activity of SET1 complexes and the role of the key subunits, WDR5, RbBP5, ASH2...

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Detalles Bibliográficos
Autores principales:	Vedadi, Masoud, Blazer, Levi, Eram, Mohammad S., Barsyte‐Lovejoy, Dalia, Arrowsmith, Cheryl H., Hajian, Taraneh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368065/ https://www.ncbi.nlm.nih.gov/pubmed/28160335 http://dx.doi.org/10.1002/pro.3129

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