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Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma
Recent exciting work partly through The Cancer Genome Atlas has implicated epigenetic mechanisms including histone modifications in the development of both pediatric and adult high-grade glioma (HGG). Histone lysine methylation has emerged as an important player in regulating gene expression and chr...
Autores principales: | Williams, Maria J., Singleton, Will G. B., Lowis, Stephen P., Malik, Karim, Kurian, Kathreena M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368219/ https://www.ncbi.nlm.nih.gov/pubmed/28401060 http://dx.doi.org/10.3389/fonc.2017.00045 |
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