Cargando…
ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration
Excessive reactive oxygen species (ROS) generation in degenerative intervertebral disc (IVD) indicates the contribution of oxidative stress to IVD degeneration (IDD), giving a novel insight into the pathogenesis of IDD. ROS are crucial intermediators in the signaling network of disc cells. They regu...
Autores principales: | Feng, Chencheng, Yang, Minghui, Lan, Minghong, Liu, Chang, Zhang, Yang, Huang, Bo, Liu, Huan, Zhou, Yue |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368368/ https://www.ncbi.nlm.nih.gov/pubmed/28392887 http://dx.doi.org/10.1155/2017/5601593 |
Ejemplares similares
-
Transcriptome and alternative splicing analysis of nucleus pulposus cells in response to high oxygen tension: Involvement of high oxygen tension in the pathogenesis of intervertebral disc degeneration
por: Feng, Chencheng, et al.
Publicado: (2018) -
Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways
por: Feng, Chencheng, et al.
Publicado: (2016) -
Cartilage intermediate layer protein affects the progression of intervertebral disc degeneration by regulating the extracellular microenvironment (Review)
por: Liu, Libangxi, et al.
Publicado: (2021) -
Oxygen-Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF-κB Pathways
por: Feng, Chencheng, et al.
Publicado: (2017) -
Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
por: Le Maitre, Christine Lyn, et al.
Publicado: (2007)