Tyrosine Phosphorylation of NR2B Contributes to Chronic Migraines via Increased Expression of CGRP in Rats

Tyrosine phosphorylation of NR2B (NR2B-pTyr), a subunit of the N-methyl-D-aspartate (NMDA) receptor, has been reported to develop central sensitization and persistent pain in the spine, but its effect in chronic migraines has not been examined. We hypothesized that tyrosine phosphorylation of NR2B c...

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Detalles Bibliográficos
Autores principales: Liang, Xiping, Wang, Sha, Qin, Guangcheng, Xie, Jingmei, Tan, Ge, Zhou, Jiying, McBride, Devin W., Chen, Lixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368391/
https://www.ncbi.nlm.nih.gov/pubmed/28393079
http://dx.doi.org/10.1155/2017/7203458

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