Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants

Heterologous prime-boosting with viral vectors encoding the pre-erythrocytic antigen thrombospondin-related adhesion protein fused to a multiple epitope string (ME-TRAP) induces CD8(+) T cell-mediated immunity to malaria sporozoite challenge in European malaria-naive and Kenyan semi-immune adults. T...

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Detalles Bibliográficos
Autores principales: Bliss, Carly M., Drammeh, Abdoulie, Bowyer, Georgina, Sanou, Guillaume S., Jagne, Ya Jankey, Ouedraogo, Oumarou, Edwards, Nick J., Tarama, Casimir, Ouedraogo, Nicolas, Ouedraogo, Mireille, Njie-Jobe, Jainaba, Diarra, Amidou, Afolabi, Muhammed O., Tiono, Alfred B., Yaro, Jean Baptiste, Adetifa, Uche J., Hodgson, Susanne H., Anagnostou, Nicholas A., Roberts, Rachel, Duncan, Christopher J.A., Cortese, Riccardo, Viebig, Nicola K., Leroy, Odile, Lawrie, Alison M., Flanagan, Katie L., Kampmann, Beate, Imoukhuede, Egeruan B., Sirima, Sodiomon B., Bojang, Kalifa, Hill, Adrian V.S., Nébié, Issa, Ewer, Katie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368405/
https://www.ncbi.nlm.nih.gov/pubmed/28153101
http://dx.doi.org/10.1016/j.ymthe.2016.11.003

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