Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine

Cancer cells reprogram their metabolism, altering both uptake and utilization of extracellular nutrients. We individually depleted amino acid nutrients from isogenic cells expressing commonly activated oncogenes to identify correspondences between nutrient supply and viability. In HME (human mammary...

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Detalles Bibliográficos
Autores principales: Poursaitidis, Ioannis, Wang, Xiaomeng, Crighton, Thomas, Labuschagne, Christiaan, Mason, David, Cramer, Shira L., Triplett, Kendra, Roy, Rajat, Pardo, Olivier E., Seckl, Michael J., Rowlinson, Scott W., Stone, Everett, Lamb, Richard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368412/
https://www.ncbi.nlm.nih.gov/pubmed/28297659
http://dx.doi.org/10.1016/j.celrep.2017.02.054

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