Unconventional Targeting of a Thiol Peroxidase to the Mitochondrial Intermembrane Space Facilitates Oxidative Protein Folding

Thiol peroxidases are conserved hydrogen peroxide scavenging and signaling molecules that contain redox-active cysteine residues. We show here that Gpx3, the major H(2)O(2) sensor in yeast, is present in the mitochondrial intermembrane space (IMS), where it serves a compartment-specific role in oxid...

Descripción completa

Detalles Bibliográficos
Autores principales: Kritsiligkou, Paraskevi, Chatzi, Afroditi, Charalampous, Georgia, Mironov, Aleksandr, Grant, Chris M., Tokatlidis, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368413/
https://www.ncbi.nlm.nih.gov/pubmed/28297675
http://dx.doi.org/10.1016/j.celrep.2017.02.053

Ejemplares similares

Ejemplares similares