HIV-1 Conserved Mosaics Delivered by Regimens with Integration-Deficient DC-Targeting Lentiviral Vector Induce Robust T Cells

To be effective against HIV type 1 (HIV-1), vaccine-induced T cells must selectively target epitopes, which are functionally conserved (present in the majority of currently circulating and reactivated HIV-1 strains) and, at the same time, beneficial (responses to which are associated with better cli...

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Detalles Bibliográficos
Autores principales: Wee, Edmund G., Ondondo, Beatrice, Berglund, Peter, Archer, Jacob, McMichael, Andrew J., Baltimore, David, ter Meulen, Jan H., Hanke, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368423/
https://www.ncbi.nlm.nih.gov/pubmed/28153096
http://dx.doi.org/10.1016/j.ymthe.2016.12.004

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