A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells

A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO(3)(−)/SO(3)(2−)). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited so...

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Detalles Bibliográficos
Autores principales: Li, Dong-Peng, Wang, Zhao-Yang, Cui, Jie, Wang, Xin, Miao, Jun-Ying, Zhao, Bao-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368602/
https://www.ncbi.nlm.nih.gov/pubmed/28349998
http://dx.doi.org/10.1038/srep45294
Descripción
Sumario:A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO(3)(−)/SO(3)(2−)). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited some desirable properties including fast response (within 2 minutes), good selectivity and high sensitivity. Moreover, the probe could detect endogenous HSO(3)(−) in liver cancer cells rather than normal liver cells, implying the diagnosal potential of the probe.

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