A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells

A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO(3)(−)/SO(3)(2−)). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited so...

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Autores principales: Li, Dong-Peng, Wang, Zhao-Yang, Cui, Jie, Wang, Xin, Miao, Jun-Ying, Zhao, Bao-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368602/
https://www.ncbi.nlm.nih.gov/pubmed/28349998
http://dx.doi.org/10.1038/srep45294
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author Li, Dong-Peng
Wang, Zhao-Yang
Cui, Jie
Wang, Xin
Miao, Jun-Ying
Zhao, Bao-Xiang
author_facet Li, Dong-Peng
Wang, Zhao-Yang
Cui, Jie
Wang, Xin
Miao, Jun-Ying
Zhao, Bao-Xiang
author_sort Li, Dong-Peng
collection PubMed
description A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO(3)(−)/SO(3)(2−)). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited some desirable properties including fast response (within 2 minutes), good selectivity and high sensitivity. Moreover, the probe could detect endogenous HSO(3)(−) in liver cancer cells rather than normal liver cells, implying the diagnosal potential of the probe.
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spelling pubmed-53686022017-03-30 A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells Li, Dong-Peng Wang, Zhao-Yang Cui, Jie Wang, Xin Miao, Jun-Ying Zhao, Bao-Xiang Sci Rep Article A new ratiometric fluorescent probe was constructed with hemicyanine and 7-nitrobenzofurazan for detection of sulfur dioxide derivatives (HSO(3)(−)/SO(3)(2−)). The ratiometric response mode could be attributed to the efficient FRET (Förster resonance energy transfer) platform. The probe exbihited some desirable properties including fast response (within 2 minutes), good selectivity and high sensitivity. Moreover, the probe could detect endogenous HSO(3)(−) in liver cancer cells rather than normal liver cells, implying the diagnosal potential of the probe. Nature Publishing Group 2017-03-28 /pmc/articles/PMC5368602/ /pubmed/28349998 http://dx.doi.org/10.1038/srep45294 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Li, Dong-Peng
Wang, Zhao-Yang
Cui, Jie
Wang, Xin
Miao, Jun-Ying
Zhao, Bao-Xiang
A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells
title A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells
title_full A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells
title_fullStr A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells
title_full_unstemmed A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells
title_short A new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells
title_sort new fluorescent probe for colorimetric and ratiometric detection of sulfur dioxide derivatives in liver cancer cells
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368602/
https://www.ncbi.nlm.nih.gov/pubmed/28349998
http://dx.doi.org/10.1038/srep45294
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