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Tailored treatment of intestinal angiodysplasia in elderly

BACKGROUND: Angiodysplasia of the gastrointestinal tract is an uncommon, but not rare, cause of bleeding and severe anemia in elderly. Different treatments exist for this kind of pathology. METHODS: The aim of this work was to study 40 patients treated for intestinal angiodysplasia with two differen...

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Autores principales: Compagna, Rita, Serra, Raffaele, Sivero, Luigi, Quarto, Gennaro, Vigliotti, Gabriele, Bianco, Tommaso, Rocca, Aldo, Amato, Maurizio, Danzi, Michele, Furino, Ermenegildo, Milone, Marco, Amato, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter Open 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368880/
https://www.ncbi.nlm.nih.gov/pubmed/28352751
http://dx.doi.org/10.1515/med-2015-0091
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author Compagna, Rita
Serra, Raffaele
Sivero, Luigi
Quarto, Gennaro
Vigliotti, Gabriele
Bianco, Tommaso
Rocca, Aldo
Amato, Maurizio
Danzi, Michele
Furino, Ermenegildo
Milone, Marco
Amato, Bruno
author_facet Compagna, Rita
Serra, Raffaele
Sivero, Luigi
Quarto, Gennaro
Vigliotti, Gabriele
Bianco, Tommaso
Rocca, Aldo
Amato, Maurizio
Danzi, Michele
Furino, Ermenegildo
Milone, Marco
Amato, Bruno
author_sort Compagna, Rita
collection PubMed
description BACKGROUND: Angiodysplasia of the gastrointestinal tract is an uncommon, but not rare, cause of bleeding and severe anemia in elderly. Different treatments exist for this kind of pathology. METHODS: The aim of this work was to study 40 patients treated for intestinal angiodysplasia with two different kind of endoscopic treatments: argon plasma coagulation (APC) and bipolar electrocoagulation (BEC). RESULTS: Age of patients was similar in both groups (76,2 ± 10.8 years vs 74,8 ± 8,7 years, P = 0,005). Angiodysplasia treated were located in small bowel, right colon, left colon, transverse colon and cecum. We analysed number of treatment, recurrence, hospital discharge, needs of blood transfusions before and after endoscopic treatment. Number of treatment was the same in both groups (1,2 ± 0,2 vs 1,1 ± 0,1, P < 0,001). We had more recurrence in patients treated with BEC (4/20 vs 2/20, P < 0,001). Hospital discharge was comparable in both groups (5,3 ± 3,1 days vs 5,4 ± 2,8 years, P < 0.001) CONCLUSIONS: Treatment of angiodysplasia in elderly is not easy. Different kinds of treatment could be adopted. APC and BEC are both safe and effective. The choice of a treatment should consider several factors: age, comorbidity, source of bleeding. In conclusion we think that treatment of bleeding for angiodysplasia in elder population should be a tailored treatment.
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spelling pubmed-53688802017-03-28 Tailored treatment of intestinal angiodysplasia in elderly Compagna, Rita Serra, Raffaele Sivero, Luigi Quarto, Gennaro Vigliotti, Gabriele Bianco, Tommaso Rocca, Aldo Amato, Maurizio Danzi, Michele Furino, Ermenegildo Milone, Marco Amato, Bruno Open Med (Wars) Research Article BACKGROUND: Angiodysplasia of the gastrointestinal tract is an uncommon, but not rare, cause of bleeding and severe anemia in elderly. Different treatments exist for this kind of pathology. METHODS: The aim of this work was to study 40 patients treated for intestinal angiodysplasia with two different kind of endoscopic treatments: argon plasma coagulation (APC) and bipolar electrocoagulation (BEC). RESULTS: Age of patients was similar in both groups (76,2 ± 10.8 years vs 74,8 ± 8,7 years, P = 0,005). Angiodysplasia treated were located in small bowel, right colon, left colon, transverse colon and cecum. We analysed number of treatment, recurrence, hospital discharge, needs of blood transfusions before and after endoscopic treatment. Number of treatment was the same in both groups (1,2 ± 0,2 vs 1,1 ± 0,1, P < 0,001). We had more recurrence in patients treated with BEC (4/20 vs 2/20, P < 0,001). Hospital discharge was comparable in both groups (5,3 ± 3,1 days vs 5,4 ± 2,8 years, P < 0.001) CONCLUSIONS: Treatment of angiodysplasia in elderly is not easy. Different kinds of treatment could be adopted. APC and BEC are both safe and effective. The choice of a treatment should consider several factors: age, comorbidity, source of bleeding. In conclusion we think that treatment of bleeding for angiodysplasia in elder population should be a tailored treatment. De Gruyter Open 2015-12-17 /pmc/articles/PMC5368880/ /pubmed/28352751 http://dx.doi.org/10.1515/med-2015-0091 Text en © 2015 Rita Compagna et al. http://creativecommons.org/licenses/by-nc-nd/3.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License.
spellingShingle Research Article
Compagna, Rita
Serra, Raffaele
Sivero, Luigi
Quarto, Gennaro
Vigliotti, Gabriele
Bianco, Tommaso
Rocca, Aldo
Amato, Maurizio
Danzi, Michele
Furino, Ermenegildo
Milone, Marco
Amato, Bruno
Tailored treatment of intestinal angiodysplasia in elderly
title Tailored treatment of intestinal angiodysplasia in elderly
title_full Tailored treatment of intestinal angiodysplasia in elderly
title_fullStr Tailored treatment of intestinal angiodysplasia in elderly
title_full_unstemmed Tailored treatment of intestinal angiodysplasia in elderly
title_short Tailored treatment of intestinal angiodysplasia in elderly
title_sort tailored treatment of intestinal angiodysplasia in elderly
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368880/
https://www.ncbi.nlm.nih.gov/pubmed/28352751
http://dx.doi.org/10.1515/med-2015-0091
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