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PMS2 gene mutation results in DNA mismatch repair system failure in a case of adult granulosa cell tumor
BACKGROUND: Granulosa cell tumors are rare ovarian malignancies. Their characteristics include unpredictable indolent growth with malignant potential and late recurrence. Approximately 95% are of adult type. Recent molecular studies have characterized the FOXL2 402C > G mutation in adult granulos...
Autores principales: | Wang, Wen-Chung, Lee, Ya-Ting, Lai, Yen-Chein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369012/ https://www.ncbi.nlm.nih.gov/pubmed/28347324 http://dx.doi.org/10.1186/s13048-017-0317-4 |
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