Evaluation and Optimization of in silico designed Sphingosine-1-Phosphate (S1P) Receptor Subtype 1 Modulators for the Management of Multiple Sclerosis

Multiple Sclerosis (MS) is a chronic autoimmune disorder affecting the Central Nervous System (CNS) through inflammation, demyelination and neurodegeneration. Sphingosine-1-phosphate receptor (S1PR1) modulators have been approved for the management of MS. Phosphorylated fingolimod mimics endogenous...

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Detalles Bibliográficos
Autores principales: Gusman, Daphne H., Shoemake, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2017
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369033/
https://www.ncbi.nlm.nih.gov/pubmed/28356890

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