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Induction of Neuroendocrine Differentiation in Prostate Cancer Cells by Dovitinib (TKI-258) and its Therapeutic Implications

Prostate cancer (PCa) remains the second-leading cause of cancer-related deaths in American men with an estimated mortality of more than 26,000 in 2016 alone. Aggressive and metastatic tumors are treated with androgen deprivation therapies (ADT); however, the tumors acquire resistance and develop in...

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Detalles Bibliográficos
Autores principales: Yadav, Shalini S., Li, Jinyi, Stockert, Jennifer A., Herzog, Bryan, O'Connor, James, Garzon-Manco, Luis, Parsons, Ramon, Tewari, Ashutosh K., Yadav, Kamlesh K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369368/
https://www.ncbi.nlm.nih.gov/pubmed/28342996
http://dx.doi.org/10.1016/j.tranon.2017.01.011