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Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control study

BACKGROUND: Alzheimer disease (AD) is a progressive disorder that affects cognitive function. There is increasing support for the role of neuroinflammation and aberrant immune regulation in the pathophysiology of AD. The immunoregulatory human leukocyte antigen (HLA) complex has been linked to susce...

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Detalles Bibliográficos
Autores principales:	Steele, Natasha Z. R., Carr, Jessie S., Bonham, Luke W., Geier, Ethan G., Damotte, Vincent, Miller, Zachary A., Desikan, Rahul S., Boehme, Kevin L., Mukherjee, Shubhabrata, Crane, Paul K., Kauwe, John S. K., Kramer, Joel H., Miller, Bruce L., Coppola, Giovanni, Hollenbach, Jill A., Huang, Yadong, Yokoyama, Jennifer S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369701/ https://www.ncbi.nlm.nih.gov/pubmed/28350795 http://dx.doi.org/10.1371/journal.pmed.1002272

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