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Optimization and evaluation of astragalus polysaccharide injectable thermoresponsive in-situ gels
The objective of this study was to develop an injectable in situ forming gel system based on Poloxamer for sustained release of Astragalus polysaccharide (APS), thus achieved once or twice administration instead of frequent dosing during long-term treatment. The optimal formulation is 10 g APS, 18 g...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369758/ https://www.ncbi.nlm.nih.gov/pubmed/28350799 http://dx.doi.org/10.1371/journal.pone.0173949 |