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Optimization and evaluation of astragalus polysaccharide injectable thermoresponsive in-situ gels

The objective of this study was to develop an injectable in situ forming gel system based on Poloxamer for sustained release of Astragalus polysaccharide (APS), thus achieved once or twice administration instead of frequent dosing during long-term treatment. The optimal formulation is 10 g APS, 18 g...

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Detalles Bibliográficos
Autores principales: Yu, Zugong, Guo, Fanxi, Guo, Yangyang, Zhang, Zhenrui, Wu, Feng, Luo, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369758/
https://www.ncbi.nlm.nih.gov/pubmed/28350799
http://dx.doi.org/10.1371/journal.pone.0173949