Cargando…

Optimization and evaluation of astragalus polysaccharide injectable thermoresponsive in-situ gels

The objective of this study was to develop an injectable in situ forming gel system based on Poloxamer for sustained release of Astragalus polysaccharide (APS), thus achieved once or twice administration instead of frequent dosing during long-term treatment. The optimal formulation is 10 g APS, 18 g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Zugong, Guo, Fanxi, Guo, Yangyang, Zhang, Zhenrui, Wu, Feng, Luo, Xiaoqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369758/ https://www.ncbi.nlm.nih.gov/pubmed/28350799 http://dx.doi.org/10.1371/journal.pone.0173949

Ejemplares similares

Optimization and evaluation of a thermoresponsive ophthalmic in situ gel containing curcumin-loaded albumin nanoparticles
por: Lou, Jie, et al.
Publicado: (2014)

Thermoresponsive Gels
por: Taylor, M. Joan, et al.
Publicado: (2017)

Development and Evaluation of Puerarin Loaded-Albumin Nanoparticles Thermoresponsive in situ Gel for Ophthalmic Delivery
por: Hu, Lixiu, et al.
Publicado: (2022)

In Situ Forming Injectable Thermoresponsive Hydrogels for Controlled Delivery of Biomacromolecules
por: Dutta, Kingshuk, et al.
Publicado: (2020)

Nanoparticles Loaded Thermoresponsive In Situ Gel for Ocular Antibiotic Delivery against Bacterial Keratitis
por: Abbas, Muhammad Naseer, et al.
Publicado: (2022)

Photomotion of Hydrogels with Covalently Attached Azo Dye Moieties—Thermoresponsive and Non-Thermoresponsive Gels
por: Jaik, Thorben G., et al.
Publicado: (2022)

Rufinamide-Loaded Chitosan Nanoparticles in Xyloglucan-Based Thermoresponsive In Situ Gel for Direct Nose to Brain Delivery
por: Dalvi, Avantika, et al.
Publicado: (2021)

Depot injectable atorvastatin biodegradable in situ gel: development, optimization, in vitro, and in vivo evaluation
por: Ahmed, Tarek A, et al.
Publicado: (2016)

Effects of in ovo Injection of Astragalus Polysaccharide on the Intestinal Development and Mucosal Immunity in Broiler Chickens
por: Yang, Shu-bao, et al.
Publicado: (2021)

Coacervate Thermoresponsive Polysaccharide Nanoparticles as Delivery System for Piroxicam
por: Lachowicz, Dorota, et al.
Publicado: (2020)

Astragalus Polysaccharides/Chitosan Microspheres for Nasal Delivery: Preparation, Optimization, Characterization, and Pharmacodynamics
por: Wang, Saisai, et al.
Publicado: (2020)

Astragalus polysaccharide protects sepsis model rats after cecum ligation and puncture
por: Li, Jun, et al.
Publicado: (2022)

Behavior of colloidal gels made of thermoresponsive anisotropic nanoparticles
por: Yang, Long, et al.
Publicado: (2022)

Molecular Weight and Monosaccharide Composition of Astragalus Polysaccharides
por: Xu, Du-Juan, et al.
Publicado: (2008)

A Review of the Pharmacological Action of Astragalus Polysaccharide
por: Zheng, Yijun, et al.
Publicado: (2020)

Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation
por: Li, Zhi-Peng, et al.
Publicado: (2018)

Correction: Jaik et al. Photomotion of Hydrogels with Covalently Attached Azo Dye Moieties—Thermoresponsive and Non-Thermoresponsive Gels. Gels 2022, 8, 541
por: Jaik, Thorben G., et al.
Publicado: (2023)

Formulation of thermoresponsive and buccal adhesive in situ gel for treatment of oral thrush containing poorly water soluble drug bifonazole
por: Patel, Dimendra, et al.
Publicado: (2012)

Homopolymer and ABC Triblock Copolymer Mixtures for Thermoresponsive Gel Formulations
por: Constantinou, Anna P., et al.
Publicado: (2021)

Effects of Apigenin and Astragalus Polysaccharide on the Cryopreservation of Bull Semen
por: Wang, Hongtao, et al.
Publicado: (2021)

A Multi-Component Nano-Co-Delivery System Utilizing Astragalus Polysaccharides as Carriers for Improving Biopharmaceutical Properties of Astragalus Flavonoids
por: Yang, Bing, et al.
Publicado: (2023)

Astragalus Polysaccharide Injection (PG2) Normalizes the Neutrophil-to-Lymphocyte Ratio in Patients with Advanced Lung Cancer Receiving Immunotherapy
por: Tsao, Shih Ming, et al.
Publicado: (2021)

Preventing effect of astragalus polysaccharide on cardiotoxicity induced by chemotherapy of epirubicin: A pilot study
por: Li, Xiaofang, et al.
Publicado: (2022)

Synergistic protection of astragalus polysaccharides and matrine against ulcerative colitis and associated lung injury in rats
por: Yan, Xin, et al.
Publicado: (2020)

Effects of Astragalus Polysaccharides on Dysfunction of Mitochondrial Dynamics Induced by Oxidative Stress
por: Huang, Yan-Feng, et al.
Publicado: (2016)

Modulatory Effects of Astragalus Polysaccharides on T-Cell Polarization in Mice with Polymicrobial Sepsis
por: Hou, Yu-Chen, et al.
Publicado: (2015)

Astragalus Polysaccharide Protects Neurons and Stabilizes Mitochondrial in a Mouse Model of Parkinson Disease
por: Liu, Hong, et al.
Publicado: (2018)

Mitochondrial Protection and Anti-aging Activity of Astragalus Polysaccharides and Their Potential Mechanism
por: Li, Xing-Tai, et al.
Publicado: (2012)

A Novel Thermoresponsive Gel as a Potential Delivery System for Lipoxin
por: Wang, B., et al.
Publicado: (2018)

Astragalus polysaccharide promotes the release of mature granulocytes through the L-selectin signaling pathway
por: Zhang, Ping-Ping, et al.
Publicado: (2015)

Effects of Astragalus polysaccharides on memory impairment in a diabetic rat model
por: Dun, Changping, et al.
Publicado: (2016)

Pharmacokinetic study of single and multiple oral administration of glutamine in healthy Beagles
por: Guo, Fanxi, et al.
Publicado: (2022)

Wound healing effect of an Astragalus membranaceus polysaccharide and its mechanism
por: Zhao, Bingjiang, et al.
Publicado: (2017)

Effects of Astragalus Polysaccharides Nanoparticles on Cerebral Thrombosis in SD Rats
por: Sun, Qian, et al.
Publicado: (2020)

Synergist for antitumor therapy: Astragalus polysaccharides acting on immune microenvironment
por: Xu, Qian, et al.
Publicado: (2023)

Ammonium glycyrrhizin counteracts liver injury caused by lipopolysaccharide/amoxicillin-clavulanate potassium
por: Yu, Zugong, et al.
Publicado: (2017)

Injectable Hyaluronan-Based Thermoresponsive Hydrogels for Dermatological Applications
por: Gou, Si, et al.
Publicado: (2023)

Injectable Thermoresponsive Hydrogels for Cancer Therapy: Challenges and Prospects
por: Tanga, Sandrine, et al.
Publicado: (2023)

Seabuckthorn polysaccharide combined with astragalus polysaccharide ameliorate alcoholic fatty liver by regulating intestinal flora
por: Liu, Jiayue, et al.
Publicado: (2022)

Extraction condition optimization and effects of drying methods on physicochemical properties and antioxidant activities of polysaccharides from Astragalus cicer L.
por: Shang, Hongmei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vhoaocdv55ecc0c50nbqprgcmh