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Data on the effects of anti-cancer drug of resveratrol in breast cancer cells, MDA-MB-231 cells
The data here is related to the article, “Curcumin enhances poly (ADP-ribose) polymerase inhibitor sensitivity to chemotherapy in breast cancer cells” (Y.E Choi, and E. Park, 2015) [1]. The article shows that curcumin, as a natural bioactive compound, enhanced DNA damage response and induced cell de...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369870/ https://www.ncbi.nlm.nih.gov/pubmed/28377996 http://dx.doi.org/10.1016/j.dib.2017.03.029 |
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author | Park, Eunmi |
author_facet | Park, Eunmi |
author_sort | Park, Eunmi |
collection | PubMed |
description | The data here is related to the article, “Curcumin enhances poly (ADP-ribose) polymerase inhibitor sensitivity to chemotherapy in breast cancer cells” (Y.E Choi, and E. Park, 2015) [1]. The article shows that curcumin, as a natural bioactive compound, enhanced DNA damage response and induced cell death in MDA-MB-231 cells [1]. This data includes that breast cancer cells, MDA-MB-231 respond to DNA damage after UV irradiation, post to resveratrol treatment. The data shows that resveratrol treatment results in reduction of S-phase cell cycle and induction of γ-H2AX, which is a hallmark of DNA damage after UV irradiation in breast cancer cells, MDA-MB-231. Moreover, resveratrol sensitizes breast cancer cells to respond to UV treatment as a natural bioactive compound. |
format | Online Article Text |
id | pubmed-5369870 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-53698702017-04-04 Data on the effects of anti-cancer drug of resveratrol in breast cancer cells, MDA-MB-231 cells Park, Eunmi Data Brief Data Article The data here is related to the article, “Curcumin enhances poly (ADP-ribose) polymerase inhibitor sensitivity to chemotherapy in breast cancer cells” (Y.E Choi, and E. Park, 2015) [1]. The article shows that curcumin, as a natural bioactive compound, enhanced DNA damage response and induced cell death in MDA-MB-231 cells [1]. This data includes that breast cancer cells, MDA-MB-231 respond to DNA damage after UV irradiation, post to resveratrol treatment. The data shows that resveratrol treatment results in reduction of S-phase cell cycle and induction of γ-H2AX, which is a hallmark of DNA damage after UV irradiation in breast cancer cells, MDA-MB-231. Moreover, resveratrol sensitizes breast cancer cells to respond to UV treatment as a natural bioactive compound. Elsevier 2017-03-21 /pmc/articles/PMC5369870/ /pubmed/28377996 http://dx.doi.org/10.1016/j.dib.2017.03.029 Text en © 2017 Published by Elsevier Inc. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Park, Eunmi Data on the effects of anti-cancer drug of resveratrol in breast cancer cells, MDA-MB-231 cells |
title | Data on the effects of anti-cancer drug of resveratrol in breast cancer cells, MDA-MB-231 cells |
title_full | Data on the effects of anti-cancer drug of resveratrol in breast cancer cells, MDA-MB-231 cells |
title_fullStr | Data on the effects of anti-cancer drug of resveratrol in breast cancer cells, MDA-MB-231 cells |
title_full_unstemmed | Data on the effects of anti-cancer drug of resveratrol in breast cancer cells, MDA-MB-231 cells |
title_short | Data on the effects of anti-cancer drug of resveratrol in breast cancer cells, MDA-MB-231 cells |
title_sort | data on the effects of anti-cancer drug of resveratrol in breast cancer cells, mda-mb-231 cells |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369870/ https://www.ncbi.nlm.nih.gov/pubmed/28377996 http://dx.doi.org/10.1016/j.dib.2017.03.029 |
work_keys_str_mv | AT parkeunmi dataontheeffectsofanticancerdrugofresveratrolinbreastcancercellsmdamb231cells |