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GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF

The alternative reading frame protein (p14ARF/ARF) is a key determinant of cell fate, acting as a potent tumor suppressor through a p53/MDM2-dependent pathway or promoting apoptosis in a p53-independent manner. The ARF protein is mainly expressed in the nucleolus and sequestered by nucleophosmin (NP...

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Detalles Bibliográficos
Autores principales:	Lee, Sun, Cho, Young-Eun, Kim, Sang-Hoon, Kim, Yong-Jun, Park, Jae-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369963/ https://www.ncbi.nlm.nih.gov/pubmed/27323397 http://dx.doi.org/10.18632/oncotarget.9957

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