HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation

HIPK2 is a Y-regulated S/T kinase involved in various cellular processes, including cell-fate decision during development and DNA damage response. Cis-autophosphorylation in the activation-loop and trans-autophosphorylation at several S/T sites along the protein are required for HIPK2 activation, su...

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Detalles Bibliográficos
Autores principales: Verdina, Alessandra, Di Rocco, Giuliana, Virdia, Ilaria, Monteonofrio, Laura, Gatti, Veronica, Policicchio, Eleonora, Bruselles, Alessandro, Tartaglia, Marco, Soddu, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369998/
https://www.ncbi.nlm.nih.gov/pubmed/28060750
http://dx.doi.org/10.18632/oncotarget.14421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5369998/
https://www.ncbi.nlm.nih.gov/pubmed/28060750
http://dx.doi.org/10.18632/oncotarget.14421

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