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Growth differentiation factor 15 induces growth and metastasis of human liver cancer stem-like cells via AKT/GSK-3β/β-catenin signaling

Cancer stem cells in liver cancer are thought to be responsible for tumor recurrence and metastasis. However, the factors that mediate this mechanism have yet to be completely elucidated. In this study, we isolated CD13(+)CD44(+) sphere cells (SCs) derived from liver cancer tissues and SK-Hep-1 cell...

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Detalles Bibliográficos
Autores principales:	Xu, Qiong, Xu, Hai-Xu, Li, Jin-Ping, Wang, Song, Fu, Zheng, Jia, Jing, Wang, Li, Zhu, Zhi-Feng, Lu, Rong, Yao, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370015/ https://www.ncbi.nlm.nih.gov/pubmed/28199981 http://dx.doi.org/10.18632/oncotarget.15216

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