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N-acetyl-cysteine attenuates remifentanil-induced postoperative hyperalgesia via inhibiting matrix metalloproteinase-9 in dorsal root ganglia

Treatment of remifentanil-induced postoperative hyperalgesia (RIH) remains a clinical challenge because the mechanisms are not fully understood. Matrix metalloproteinase-9 (MMP-9) is a key component in neuroinflammation because of its facilitation of pro-inflammatory cytokine maturation. Therefore,...

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Detalles Bibliográficos
Autores principales:	Liu, Yue, Ni, Yuan, Zhang, Wei, Sun, Yu-E, Ma, Zhengliang, Gu, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370016/ https://www.ncbi.nlm.nih.gov/pubmed/28199982 http://dx.doi.org/10.18632/oncotarget.15217

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