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Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling

Derlin-1 has been found to be overexpressed in several human cancers. However, its clinical significance and biological roles in bladder cancer remain unexplored. Here, we found that Derlin-1 was upregulated in 38.6% (58/150) cases of cancer samples. The rate of Derlin-1 overexpression was higher in...

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Detalles Bibliográficos
Autores principales:	Dong, Qianze, Fu, Lin, Zhao, Yue, Tan, Shutao, Wang, Enhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370022/ https://www.ncbi.nlm.nih.gov/pubmed/28178653 http://dx.doi.org/10.18632/oncotarget.15001

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