Modeling amplified p53 responses under DNA-PK inhibition in DNA damage response

During DNA double strand breaks (DSBs) repair, coordinated activation of phosphatidylinositol 3-kinase (PI3K)-like kinases can activate p53 signaling pathway. Recent findings have identified novel interplays among these kinases demonstrating amplified first p53 pulses under DNA-PK inhibition. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Tingzhe, Li, Xinda, Shen, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370026/
https://www.ncbi.nlm.nih.gov/pubmed/28177883
http://dx.doi.org/10.18632/oncotarget.15062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370026/
https://www.ncbi.nlm.nih.gov/pubmed/28177883
http://dx.doi.org/10.18632/oncotarget.15062

Ejemplares similares