Cargando…

Focal adhesion kinases crucially regulate TGFβ-induced migration and invasion of bladder cancer cells via Src kinase and E-cadherin

Focal adhesion kinase (FAK) is a non-receptor protein-tyrosine kinase that is triggered off by special extracellular signals such as some growth factors and integrins. FAK is found in cell–matrix attachment sites and implicated in cell migration, invasion, movement, gene expression, survival and apo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, De-Bo, Chen, Feng, Sima, Ni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370070/ https://www.ncbi.nlm.nih.gov/pubmed/28367061 http://dx.doi.org/10.2147/OTT.S122463

Ejemplares similares

Inhibition of focal adhesion kinase induces apoptosis in bladder cancer cells via Src and the phosphatidylinositol 3-kinase/Akt pathway
por: KONG, DEBO, et al.
Publicado: (2015)

Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration
por: Wu, Jui-Chung, et al.
Publicado: (2015)

Glycogen synthase kinase 3β promotes osteosarcoma invasion and migration via regulating PTEN and phosphorylation of focal adhesion kinase
por: Mai, Wei, et al.
Publicado: (2021)

Focal Adhesion Remodeling Is Crucial for Glucose-Stimulated Insulin Secretion and Involves Activation of Focal Adhesion Kinase and Paxillin
por: Rondas, Dieter, et al.
Publicado: (2011)

Migration and invasion of NSCLC suppressed by the downregulation of Src/focal adhesion kinase using single, double and tetra domain anti- CEACAM6 antibodies
por: Wu, Shang-Jung, et al.
Publicado: (2021)

Cell Invasion by Neisseria meningitidis Requires a Functional Interplay between the Focal Adhesion Kinase, Src and Cortactin
por: Slanina, Heiko, et al.
Publicado: (2012)

Src-mediated tyrosine phosphorylation of Protein Kinase D2 at focal adhesions regulates cell adhesion
por: Durand, Nisha, et al.
Publicado: (2017)

The Role of Focal Adhesion Kinase in the TGF-β-Induced Myofibroblast Transdifferentiation of Human Tenon's Fibroblasts
por: Hong, Samin, et al.
Publicado: (2012)

miR-218 regulates focal adhesion kinase–dependent TGFβ signaling in fibroblasts
por: Guo, Fen, et al.
Publicado: (2014)

Divergent modulation of Rho‐kinase and Ca(2+) influx pathways by Src family kinases and focal adhesion kinase in airway smooth muscle
por: Shaifta, Yasin, et al.
Publicado: (2015)

Immune Cell Induced Migration of Osteoprogenitor Cells Is Mediated by TGF-β Dependent Upregulation of NOX4 and Activation of Focal Adhesion Kinase
por: Ehnert, Sabrina, et al.
Publicado: (2018)

p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy
por: Sandilands, Emma, et al.
Publicado: (2015)

Protein Kinase C, Focal Adhesions and the Regulation of Cell Migration
por: Fogh, Betina S., et al.
Publicado: (2014)

Focal adhesion kinase is involved in the migration of human osteosarcoma cells
por: Feng, Sitan, et al.
Publicado: (2021)

Src-mediated coupling of focal adhesion kinase to integrin αvβ5 in vascular endothelial growth factor signaling
por: Eliceiri, Brian P., et al.
Publicado: (2002)

Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments
por: Guo, Xiaohua, et al.
Publicado: (2020)

Effects of Electrical Stimulation on the Signal Transduction-Related Proteins, c-Src and Focal Adhesion Kinase, in Fibroblasts
por: Katoh, Kazuo
Publicado: (2022)

CdGAP maintains podocyte function and modulates focal adhesions in a Src kinase-dependent manner
por: Matsuda, Jun, et al.
Publicado: (2022)

FAK/src-Family Dependent Activation of the Ste20-Like Kinase SLK Is Required for Microtubule-Dependent Focal Adhesion Turnover and Cell Migration
por: Wagner, Simona, et al.
Publicado: (2008)

Focal Adhesion Kinases in Adhesion Structures and Disease
por: Eleniste, Pierre P., et al.
Publicado: (2012)

Y‐27632, an Inhibitor of Rho‐associated Protein Kinase, Suppresses Tumor Cell Invasion via Regulation of Focal Adhesion and Focal Adhesion Kinase
por: Imamura, Fumio, et al.
Publicado: (2000)

The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling
por: Ichikawa-Tomikawa, Naoki, et al.
Publicado: (2023)

Chemotherapy-Induced Collagen IV Drives Cancer Cell Motility through Activation of Src and Focal Adhesion Kinase
por: Fatherree, Jackson P., et al.
Publicado: (2022)

Mechanism of Focal Adhesion Kinase Mechanosensing
por: Zhou, Jing, et al.
Publicado: (2015)

V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift
Publicado: (1995)

Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
por: Masraksa, Wuttipong, et al.
Publicado: (2020)

Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation
por: Steffen, Anika, et al.
Publicado: (2013)

Recruitment of focal adhesion kinase and paxillin to β1 integrin promotes cancer cell migration via mitogen activated protein kinase activation
por: Crowe, David L, et al.
Publicado: (2004)

Activation of Rho-kinase and focal adhesion kinase regulates the organization of stress fibers and focal adhesions in the central part of fibroblasts
por: Katoh, Kazuo
Publicado: (2017)

Src Kinase Regulation in Progressively Invasive Cancer
por: Xu, Weichen, et al.
Publicado: (2012)

Focal Adhesion Kinase Promotes Hepatic Stellate Cell Activation by Regulating Plasma Membrane Localization of TGFβ Receptor 2
por: Chen, Yunru, et al.
Publicado: (2019)

SOX2 Enhances the Migration and Invasion of Ovarian Cancer Cells via Src Kinase
por: Wang, Xiaojie, et al.
Publicado: (2014)

Focal adhesion kinase and paxillin promote migration and adhesion to fibronectin by swine skeletal muscle satellite cells
por: Wang, Dan, et al.
Publicado: (2016)

Regulation of the Cell Cycle by Focal Adhesion Kinase
por: Zhao, Ji-He, et al.
Publicado: (1998)

Requirement of focal adhesion kinase in branching tubulogenesis
por: Wei, Wei-Chun, et al.
Publicado: (2009)

Emerging Roles of Focal Adhesion Kinase in Cancer
por: Tai, Yu-Ling, et al.
Publicado: (2015)

Progesterone enhances vascular endothelial cell migration via activation of focal adhesion kinase
por: Zheng, Shuhui, et al.
Publicado: (2012)

Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis
por: Shelef, Miriam A, et al.
Publicado: (2014)

Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics
por: Schober, Markus, et al.
Publicado: (2007)

The KDEL receptor signalling cascade targets focal adhesion kinase on focal adhesions and invadopodia
por: Ruggiero, Carmen, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_imqn75hvkiean1dnilltekdc92