Reduction of oxidative-nitrosative stress underlies anticataract effect of topically applied tocotrienol in streptozotocin-induced diabetic rats

Cataract, a leading cause of blindness, is of special concern in diabetics as it occurs at earlier onset. Polyol accumulation and increased oxidative-nitrosative stress in cataractogenesis are associated with NFκB activation, iNOS expression, ATP depletion, loss of ATPase functions, calpain activati...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdul Nasir, Nurul Alimah, Agarwal, Renu, Sheikh Abdul Kadir, Siti Hamimah, Vasudevan, Sushil, Tripathy, Minaketan, Iezhitsa, Igor, Mohammad Daher, Aqil, Ibrahim, Mohd Ikraam, Mohd Ismail, Nafeeza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370128/
https://www.ncbi.nlm.nih.gov/pubmed/28350848
http://dx.doi.org/10.1371/journal.pone.0174542

Ejemplares similares

Ejemplares similares