Cargando…
PKD knockdown inhibits pressure overload-induced cardiac hypertrophy by promoting autophagy via AKT/mTOR pathway
Growing evidence shows that protein kinase D (PKD) plays an important role in the development of pressure overload-induced cardiac hypertrophy. However, the mechanisms involved are not clear. This study tested our hypothesis that PKD might mediate cardiac hypertrophy by negatively regulating autopha...
Autores principales: | Zhao, Di, Wang, Wei, Wang, Hao, Peng, Honghai, Liu, Xiangjuan, Guo, Weixing, Su, Guohai, Zhao, Zhuo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370435/ https://www.ncbi.nlm.nih.gov/pubmed/28367092 http://dx.doi.org/10.7150/ijbs.17617 |
Ejemplares similares
-
G Protein-Coupled Estrogen Receptor 1 Inhibits Angiotensin II-Induced Cardiomyocyte Hypertrophy via the Regulation of PI3K-Akt-mTOR Signalling and Autophagy
por: Pei, Hui, et al.
Publicado: (2019) -
The Akt-mTOR axis is a pivotal regulator of eccentric hypertrophy during volume overload
por: Ikeda, Masataka, et al.
Publicado: (2015) -
Peroxiredoxin-5 Knockdown Accelerates Pressure Overload-Induced Cardiac Hypertrophy in Mice
por: Hu, Chengyun, et al.
Publicado: (2022) -
Intermedin Suppresses Pressure Overload Cardiac Hypertrophy through Activation of Autophagy
por: Chen, HuaLi, et al.
Publicado: (2013) -
Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway
por: Yang, Jinjing, et al.
Publicado: (2018)