PADI4 Epigenetically Suppresses p21 Transcription and Inhibits Cell Apoptosis in Fibroblast-like Synoviocytes from Rheumatoid Arthritis Patients

Rheumatoid arthritis (RA) is characterized by synovial lining hyperplasia, which involves abnormal growth of fibroblast-like synoviocytes (FLSs). This study aimed to investigate the function and molecular mechanism of peptidylarginine deiminase type 4 (PADI4) in FLSs isolated from RA patients (RA-FL...

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Detalles Bibliográficos
Autores principales: Fan, Lieying, Zong, Ming, Gong, Ruhan, He, Dongyi, Li, Niu, Sun, Li shan, Ye, Qin, Yu, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370443/
https://www.ncbi.nlm.nih.gov/pubmed/28367100
http://dx.doi.org/10.7150/ijbs.16879

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