PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings

A 67-year-old man diagnosed with Gleason score 4 + 5 = 9 clinically localized prostate cancer with (68)Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) positive Paget bone disease is described. Immunohistochemical staining r...

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Detalles Bibliográficos
Autores principales: Froehner, Michael, Toma, Marieta, Zöphel, Klaus, Novotny, Vladimir, Laniado, Michael, Wirth, Manfred P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370467/
https://www.ncbi.nlm.nih.gov/pubmed/28396816
http://dx.doi.org/10.1155/2017/1654231
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author Froehner, Michael
Toma, Marieta
Zöphel, Klaus
Novotny, Vladimir
Laniado, Michael
Wirth, Manfred P.
author_facet Froehner, Michael
Toma, Marieta
Zöphel, Klaus
Novotny, Vladimir
Laniado, Michael
Wirth, Manfred P.
author_sort Froehner, Michael
collection PubMed
description A 67-year-old man diagnosed with Gleason score 4 + 5 = 9 clinically localized prostate cancer with (68)Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) positive Paget bone disease is described. Immunohistochemical staining revealed weak PSMA positivity of the bone lesion supporting the hypothesis that neovasculature might explain positive PSMA-PET/CT findings in Paget disease.
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spelling pubmed-53704672017-04-10 PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings Froehner, Michael Toma, Marieta Zöphel, Klaus Novotny, Vladimir Laniado, Michael Wirth, Manfred P. Case Rep Urol Case Report A 67-year-old man diagnosed with Gleason score 4 + 5 = 9 clinically localized prostate cancer with (68)Ga-labeled prostate-specific membrane antigen-targeted ligand positron emission tomography/computed tomography (PSMA-PET/CT) positive Paget bone disease is described. Immunohistochemical staining revealed weak PSMA positivity of the bone lesion supporting the hypothesis that neovasculature might explain positive PSMA-PET/CT findings in Paget disease. Hindawi 2017 2017-03-15 /pmc/articles/PMC5370467/ /pubmed/28396816 http://dx.doi.org/10.1155/2017/1654231 Text en Copyright © 2017 Michael Froehner et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Froehner, Michael
Toma, Marieta
Zöphel, Klaus
Novotny, Vladimir
Laniado, Michael
Wirth, Manfred P.
PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings
title PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings
title_full PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings
title_fullStr PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings
title_full_unstemmed PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings
title_short PSMA-PET/CT-Positive Paget Disease in a Patient with Newly Diagnosed Prostate Cancer: Imaging and Bone Biopsy Findings
title_sort psma-pet/ct-positive paget disease in a patient with newly diagnosed prostate cancer: imaging and bone biopsy findings
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370467/
https://www.ncbi.nlm.nih.gov/pubmed/28396816
http://dx.doi.org/10.1155/2017/1654231
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