Cargando…

Regulation of protein and mRNA expression of the mTORC1 repressor REDD1 in response to leucine and serum

Expression of the mTORC1 repressor, Regulated in DNA Damage and Development 1 (REDD1), is elevated in skeletal muscle during various catabolic conditions including fasting, hindlimb immobilization, and sepsis. Conversely, REDD1 expression is suppressed by anabolic stimuli such as resistance exercise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Black, Adam J., Gordon, Bradley S., Dennis, Michael D., Jefferson, Leonard S., Kimball, Scot R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370564/ https://www.ncbi.nlm.nih.gov/pubmed/28367506 http://dx.doi.org/10.1016/j.bbrep.2016.10.003

Ejemplares similares

Repressors of mTORC1 act to blunt the anabolic response to feeding in the soleus muscle of a cast‐immobilized mouse hindlimb
por: Shimkus, Kevin L., et al.
Publicado: (2018)

Changes in REDD1, REDD2, and atrogene mRNA expression are prevented in skeletal muscle fixed in a stretched position during hindlimb immobilization
por: Kelleher, Andrew R., et al.
Publicado: (2014)

Amino Acid–Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet
por: Kimball, Scot R, et al.
Publicado: (2015)

mTORC1 Dependent Regulation of REDD1 Protein Stability
por: Tan, Chia Yee, et al.
Publicado: (2013)

mTORC1-Independent Reduction of Retinal Protein Synthesis in Type 1 Diabetes
por: Fort, Patrice E., et al.
Publicado: (2014)

Differential regulation of mTORC1 by leucine and glutamine
por: Jewell, Jenna L., et al.
Publicado: (2015)

FLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1
por: Wu, Xiaochun, et al.
Publicado: (2016)

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
por: Tang, Haiyang, et al.
Publicado: (2018)

Inhibition of mTORC1 through ATF4-induced REDD1 and Sestrin2 expression by Metformin
por: Jang, Se-Kyeong, et al.
Publicado: (2021)

mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016)

Leucine regulates autophagy via acetylation of the mTORC1 component raptor
por: Son, Sung Min, et al.
Publicado: (2020)

Co-ingestion of glutamine and leucine synergistically promotes mTORC1 activation
por: Yoshimura, Ryoji, et al.
Publicado: (2022)

Resistance exercise enhances long-term mTORC1 sensitivity to leucine
por: D'Hulst, Gommaar, et al.
Publicado: (2022)

Endurance exercise induces REDD1 expression and transiently decreases mTORC1 signaling in rat skeletal muscle
por: Hayasaka, Miki, et al.
Publicado: (2014)

Iron chelation inhibits mTORC1 signaling involving activation of AMPK and REDD1/Bnip3 pathways
por: Shang, Chaowei, et al.
Publicado: (2020)

Correction to: Inhibition of mTORC1 through ATF4-induced REDD1 and Sestrin2 expression by Metformin
por: Jang, Se-Kyeong, et al.
Publicado: (2021)

Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2
por: Kosillo, Polina, et al.
Publicado: (2022)

Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2
por: Luo, Yan, et al.
Publicado: (2015)

Stimulation of mTORC1 with L-leucine Rescues Defects Associated with Roberts Syndrome
por: Xu, Baoshan, et al.
Publicado: (2013)

Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome
por: Xu, Baoshan, et al.
Publicado: (2016)

Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
por: Son, Sung Min, et al.
Publicado: (2019)

Iron depletion suppresses mTORC1-directed signalling in intestinal Caco-2 cells via induction of REDD1
por: Watson, Ailsa, et al.
Publicado: (2016)

Autophagy regulated by the HIF/REDD1/mTORC1 signaling is progressively increased during erythroid differentiation under hypoxia
por: Li, Jian, et al.
Publicado: (2022)

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion
por: Chen, Long, et al.
Publicado: (2015)

The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
por: Merhi, Ahmad, et al.
Publicado: (2017)

Ursolic Acid Inhibits Leucine-Stimulated mTORC1 Signaling by Suppressing mTOR Localization to Lysosome
por: Ou, Xiang, et al.
Publicado: (2014)

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
por: Ding, Xiaolei, et al.
Publicado: (2016)

LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion
por: Ribeiro, Marcelle C., et al.
Publicado: (2018)

mTORC1 and mTORC2 differentially promote natural killer cell development
por: Yang, Chao, et al.
Publicado: (2018)

mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV
por: Yang, Jin Young, et al.
Publicado: (2019)

mTORC2, but not mTORC1, is required for hippocampal mGluR-LTD and associated behaviors
por: Zhu, Ping Jun, et al.
Publicado: (2018)

Glutaminolysis feeds mTORC1
por: Durán, Raúl V., et al.
Publicado: (2012)

Regulation of adiposity by mTORC1
por: Magdalon, Juliana, et al.
Publicado: (2017)

Regulation of Autophagy through TORC1 and mTORC1
por: Noda, Takeshi
Publicado: (2017)

A unifying model for mTORC1-mediated regulation of mRNA translation
por: Thoreen, Carson C., et al.
Publicado: (2012)

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
por: Feldman, Morris E, et al.
Publicado: (2009)

The crosstalk between MYC and mTORC1 during osteoclastogenesis
por: Bae, Seyeon, et al.
Publicado: (2022)

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control
por: Gan, Wenjian, et al.
Publicado: (2020)

TLR4 counteracts BVRA signaling in human leukocytes via differential regulation of AMPK, mTORC1 and mTORC2
por: Zhang, Zhiyong, et al.
Publicado: (2019)

mTORC1 and mTORC2 Differentially Regulate Cell Fate Programs to Coordinate Osteoblastic Differentiation in Mesenchymal Stromal Cells
por: Schaub, Theres, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5qs8bkmdl425u8euh6v4m16tpd