Epigenetic aging signatures in mice livers are slowed by dwarfism, calorie restriction and rapamycin treatment

BACKGROUND: Global but predictable changes impact the DNA methylome as we age, acting as a type of molecular clock. This clock can be hastened by conditions that decrease lifespan, raising the question of whether it can also be slowed, for example, by conditions that increase lifespan. Mice are part...

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Detalles Bibliográficos
Autores principales: Wang, Tina, Tsui, Brian, Kreisberg, Jason F., Robertson, Neil A., Gross, Andrew M., Yu, Michael Ku, Carter, Hannah, Brown-Borg, Holly M., Adams, Peter D., Ideker, Trey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371228/
https://www.ncbi.nlm.nih.gov/pubmed/28351423
http://dx.doi.org/10.1186/s13059-017-1186-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371228/
https://www.ncbi.nlm.nih.gov/pubmed/28351423
http://dx.doi.org/10.1186/s13059-017-1186-2

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