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CIDR: Ultrafast and accurate clustering through imputation for single-cell RNA-seq data

Most existing dimensionality reduction and clustering packages for single-cell RNA-seq (scRNA-seq) data deal with dropouts by heavy modeling and computational machinery. Here, we introduce CIDR (Clustering through Imputation and Dimensionality Reduction), an ultrafast algorithm that uses a novel yet...

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Detalles Bibliográficos
Autores principales: Lin, Peijie, Troup, Michael, Ho, Joshua W. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371246/
https://www.ncbi.nlm.nih.gov/pubmed/28351406
http://dx.doi.org/10.1186/s13059-017-1188-0