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Can we use gonadotropin plasma concentration as surrogate marker for BMI-related incomplete estrogen suppression in breast cancer patients receiving anastrozole?
BACKGROUND: BMI has been suggested to impact on estrogenic activity in patients receiving anastrozole resulting in a reduced treatment efficacy in obese women. Current evidence in this regard is controversially discussed. Since estradiol is inversely correlated with gonadotropins it can be assumed t...
Autores principales: | Oberguggenberger, A., Meraner, V., Sztankay, M., Beer, B., Weigel, G., Oberacher, H., Kemmler, G., Czech, T., Holzner, B., Wildt, L., Sperner-Unterweger, B., Daniaux, M., Hubalek, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371265/ https://www.ncbi.nlm.nih.gov/pubmed/28351392 http://dx.doi.org/10.1186/s12885-017-3208-6 |
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