The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivo

BACKGROUND: ELF2 (E74-like factor 2) also known as NERF (new Ets-related factor), a member of the Ets family of transcription factors, regulates genes important in B and T cell development, cell cycle progression, and angiogenesis. Conserved ELF2 isoforms, ELF2A, and ELF2B, arising from alternative...

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Detalles Bibliográficos
Autores principales: Guan, Fiona H. X., Bailey, Charles G., Metierre, Cynthia, O’Young, Patrick, Gao, Dadi, Khoo, Teh Liane, Holst, Jeff, Rasko, John E. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371273/
https://www.ncbi.nlm.nih.gov/pubmed/28351373
http://dx.doi.org/10.1186/s13045-017-0446-7

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