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Investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics

It is well known that pure-tone audiometry does not sufficiently describe individual hearing loss (HL) and that additional measures beyond pure-tone sensitivity might improve the diagnostics of hearing deficits. Specifically, forward masking experiments to estimate basilar-membrane (BM) input-output...

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Autores principales: Fereczkowski, Michal, Jepsen, Morten L., Dau, Torsten, MacDonald, Ewen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371388/
https://www.ncbi.nlm.nih.gov/pubmed/28355275
http://dx.doi.org/10.1371/journal.pone.0174776
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author Fereczkowski, Michal
Jepsen, Morten L.
Dau, Torsten
MacDonald, Ewen N.
author_facet Fereczkowski, Michal
Jepsen, Morten L.
Dau, Torsten
MacDonald, Ewen N.
author_sort Fereczkowski, Michal
collection PubMed
description It is well known that pure-tone audiometry does not sufficiently describe individual hearing loss (HL) and that additional measures beyond pure-tone sensitivity might improve the diagnostics of hearing deficits. Specifically, forward masking experiments to estimate basilar-membrane (BM) input-output (I/O) function have been proposed. However, such measures are very time consuming. The present study investigated possible modifications of the temporal masking curve (TMC) paradigm to improve time and measurement efficiency. In experiment 1, estimates of knee point (KP) and compression ratio (CR) of individual BM I/Os were derived without considering the corresponding individual “off-frequency” TMC. While accurate estimation of KPs was possible, it is difficult to ensure that the tested dynamic range is sufficient. Therefore, in experiment 2, a TMC-based paradigm, referred to as the “gap method”, was tested. In contrast to the standard TMC paradigm, the maker level was kept fixed and the “gap threshold” was obtained, such that the masker just masks a low-level (12 dB sensation level) signal. It is argued that this modification allows for better control of the tested stimulus level range, which appears to be the main drawback of the conventional TMC method. The results from the present study were consistent with the literature when estimating KP levels, but showed some limitations regarding the estimation of the CR values. Perspectives and limitations of both approaches are discussed.
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spelling pubmed-53713882017-04-07 Investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics Fereczkowski, Michal Jepsen, Morten L. Dau, Torsten MacDonald, Ewen N. PLoS One Research Article It is well known that pure-tone audiometry does not sufficiently describe individual hearing loss (HL) and that additional measures beyond pure-tone sensitivity might improve the diagnostics of hearing deficits. Specifically, forward masking experiments to estimate basilar-membrane (BM) input-output (I/O) function have been proposed. However, such measures are very time consuming. The present study investigated possible modifications of the temporal masking curve (TMC) paradigm to improve time and measurement efficiency. In experiment 1, estimates of knee point (KP) and compression ratio (CR) of individual BM I/Os were derived without considering the corresponding individual “off-frequency” TMC. While accurate estimation of KPs was possible, it is difficult to ensure that the tested dynamic range is sufficient. Therefore, in experiment 2, a TMC-based paradigm, referred to as the “gap method”, was tested. In contrast to the standard TMC paradigm, the maker level was kept fixed and the “gap threshold” was obtained, such that the masker just masks a low-level (12 dB sensation level) signal. It is argued that this modification allows for better control of the tested stimulus level range, which appears to be the main drawback of the conventional TMC method. The results from the present study were consistent with the literature when estimating KP levels, but showed some limitations regarding the estimation of the CR values. Perspectives and limitations of both approaches are discussed. Public Library of Science 2017-03-29 /pmc/articles/PMC5371388/ /pubmed/28355275 http://dx.doi.org/10.1371/journal.pone.0174776 Text en © 2017 Fereczkowski et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Fereczkowski, Michal
Jepsen, Morten L.
Dau, Torsten
MacDonald, Ewen N.
Investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics
title Investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics
title_full Investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics
title_fullStr Investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics
title_full_unstemmed Investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics
title_short Investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics
title_sort investigating time-efficiency of forward masking paradigms for estimating basilar membrane input-output characteristics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371388/
https://www.ncbi.nlm.nih.gov/pubmed/28355275
http://dx.doi.org/10.1371/journal.pone.0174776
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