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A case report: Liraglutide as a novel treatment option in late dumping syndrome

RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgi...

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Detalles Bibliográficos
Autores principales: Chiappetta, Sonja, Stier, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371453/
https://www.ncbi.nlm.nih.gov/pubmed/28328816
http://dx.doi.org/10.1097/MD.0000000000006348
Descripción
Sumario:RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgical late dumping syndrome after Toupet fundoplication. DIAGNOSES: Sigstad Score, OGTT, CGM. INTERVENTIONS: Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg). OUTCOMES: Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events. LESSONS: Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery.