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A case report: Liraglutide as a novel treatment option in late dumping syndrome
RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371453/ https://www.ncbi.nlm.nih.gov/pubmed/28328816 http://dx.doi.org/10.1097/MD.0000000000006348 |
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author | Chiappetta, Sonja Stier, Christine |
author_facet | Chiappetta, Sonja Stier, Christine |
author_sort | Chiappetta, Sonja |
collection | PubMed |
description | RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgical late dumping syndrome after Toupet fundoplication. DIAGNOSES: Sigstad Score, OGTT, CGM. INTERVENTIONS: Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg). OUTCOMES: Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events. LESSONS: Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery. |
format | Online Article Text |
id | pubmed-5371453 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-53714532017-04-03 A case report: Liraglutide as a novel treatment option in late dumping syndrome Chiappetta, Sonja Stier, Christine Medicine (Baltimore) 4200 RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgical late dumping syndrome after Toupet fundoplication. DIAGNOSES: Sigstad Score, OGTT, CGM. INTERVENTIONS: Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg). OUTCOMES: Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events. LESSONS: Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery. Wolters Kluwer Health 2017-03-24 /pmc/articles/PMC5371453/ /pubmed/28328816 http://dx.doi.org/10.1097/MD.0000000000006348 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | 4200 Chiappetta, Sonja Stier, Christine A case report: Liraglutide as a novel treatment option in late dumping syndrome |
title | A case report: Liraglutide as a novel treatment option in late dumping syndrome |
title_full | A case report: Liraglutide as a novel treatment option in late dumping syndrome |
title_fullStr | A case report: Liraglutide as a novel treatment option in late dumping syndrome |
title_full_unstemmed | A case report: Liraglutide as a novel treatment option in late dumping syndrome |
title_short | A case report: Liraglutide as a novel treatment option in late dumping syndrome |
title_sort | case report: liraglutide as a novel treatment option in late dumping syndrome |
topic | 4200 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371453/ https://www.ncbi.nlm.nih.gov/pubmed/28328816 http://dx.doi.org/10.1097/MD.0000000000006348 |
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