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A case report: Liraglutide as a novel treatment option in late dumping syndrome

RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgi...

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Detalles Bibliográficos
Autores principales: Chiappetta, Sonja, Stier, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371453/
https://www.ncbi.nlm.nih.gov/pubmed/28328816
http://dx.doi.org/10.1097/MD.0000000000006348
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author Chiappetta, Sonja
Stier, Christine
author_facet Chiappetta, Sonja
Stier, Christine
author_sort Chiappetta, Sonja
collection PubMed
description RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgical late dumping syndrome after Toupet fundoplication. DIAGNOSES: Sigstad Score, OGTT, CGM. INTERVENTIONS: Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg). OUTCOMES: Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events. LESSONS: Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery.
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spelling pubmed-53714532017-04-03 A case report: Liraglutide as a novel treatment option in late dumping syndrome Chiappetta, Sonja Stier, Christine Medicine (Baltimore) 4200 RATIONALE: Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging. PATIENT CONCERNS: New-onset postsurgical late dumping syndrome after Toupet fundoplication. DIAGNOSES: Sigstad Score, OGTT, CGM. INTERVENTIONS: Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg). OUTCOMES: Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events. LESSONS: Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery. Wolters Kluwer Health 2017-03-24 /pmc/articles/PMC5371453/ /pubmed/28328816 http://dx.doi.org/10.1097/MD.0000000000006348 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 4200
Chiappetta, Sonja
Stier, Christine
A case report: Liraglutide as a novel treatment option in late dumping syndrome
title A case report: Liraglutide as a novel treatment option in late dumping syndrome
title_full A case report: Liraglutide as a novel treatment option in late dumping syndrome
title_fullStr A case report: Liraglutide as a novel treatment option in late dumping syndrome
title_full_unstemmed A case report: Liraglutide as a novel treatment option in late dumping syndrome
title_short A case report: Liraglutide as a novel treatment option in late dumping syndrome
title_sort case report: liraglutide as a novel treatment option in late dumping syndrome
topic 4200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371453/
https://www.ncbi.nlm.nih.gov/pubmed/28328816
http://dx.doi.org/10.1097/MD.0000000000006348
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