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Peripheral venous congestion causes time‐ and dose‐dependent release of endothelin‐1 in humans

Endothelin‐1 (ET‐1) is a pivotal mediator of vasoconstriction and inflammation in congestive states such as heart failure (HF) and chronic kidney disease (CKD). Whether peripheral venous congestion (VC) increases plasma ET‐1 at pressures commonly seen in HF and CKD patients is unknown. We seek to ch...

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Detalles Bibliográficos
Autores principales: Lin, Jeffrey, Chudasama, Neelesh, Hayashi, Yacki, Hawk, Christopher, Ramnauth, Sahadeo D., Wong, Ka Yuk, Harxhi, Ante, Onat, Duygu, Wakabayashi, Michiyori, Uriel, Nir, Jorde, Ulrich P., LeJemtel, Thierry H., Sabbah, Hani N., Demmer, Ryan T., Colombo, Paolo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371548/
https://www.ncbi.nlm.nih.gov/pubmed/28320895
http://dx.doi.org/10.14814/phy2.13118