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Your mitochondria are what you eat: a high‐fat or a high‐sucrose diet eliminates metabolic flexibility in isolated mitochondria from rat skeletal muscle

Extreme diets consisting of either high fat (HF) or high sucrose (HS) may lead to insulin resistance in skeletal muscle, often associated with mitochondrial dysfunction. However, it is not known if these diets alter normal interactions of pyruvate and fatty acid oxidation at the level of the mitocho...

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Detalles Bibliográficos
Autores principales: Jørgensen, Wenche, Rud, Kasper A., Mortensen, Ole H., Frandsen, Lis, Grunnet, Niels, Quistorff, Bjørn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371568/
https://www.ncbi.nlm.nih.gov/pubmed/28330953
http://dx.doi.org/10.14814/phy2.13207