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Investigation of Endocytic Pathways for the Internalization of Exosome-Associated Oligomeric Alpha-Synuclein
Misfolding and aggregation of alpha-synuclein (αsyn) resulting in cytotoxicity is a hallmark of Parkinson's disease (PD) and related synucleinopathies. The recent body of evidence indicates that αsyn can be released from neuronal cells by nonconventional exocytosis involving extracellular vesic...
Autores principales: | Delenclos, Marion, Trendafilova, Teodora, Mahesh, Divya, Baine, Ann M., Moussaud, Simon, Yan, Irene K., Patel, Tushar, McLean, Pamela J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371652/ https://www.ncbi.nlm.nih.gov/pubmed/28424577 http://dx.doi.org/10.3389/fnins.2017.00172 |
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