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Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment
Despite the current progresses of modern medicine, the resistance of malignant tumors to present medical treatments points to the necessity of developing new therapeutic approaches. In recent years, numerous studies have focused their attention on the promising use of nanomaterials, like iron oxide...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371782/ https://www.ncbi.nlm.nih.gov/pubmed/28212271 http://dx.doi.org/10.3390/bios7010009 |
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author | Sanginario, Alessandro Miccoli, Beatrice Demarchi, Danilo |
author_facet | Sanginario, Alessandro Miccoli, Beatrice Demarchi, Danilo |
author_sort | Sanginario, Alessandro |
collection | PubMed |
description | Despite the current progresses of modern medicine, the resistance of malignant tumors to present medical treatments points to the necessity of developing new therapeutic approaches. In recent years, numerous studies have focused their attention on the promising use of nanomaterials, like iron oxide nanowires, zinc oxide or mesoporous silica nanoparticles, for cancer and metastasis treatment with the advantage of operating directly at the bio-molecular scale. Among them, carbon nanotubes emerged as valid candidates not only for drug delivery, but also as a valuable tool in cancer imaging and physical ablation. Nevertheless, deep investigations about carbon nanotubes’ potential bio-compatibility and cytotoxicity limits should be also critically addressed. In the present review, after introducing carbon nanotubes and their promising advantages and drawbacks for fighting cancer, we want to focus on the numerous and different ways in which they can assist to reach this goal. Specifically, we report on how they can be used not only for drug delivery purposes, but also as a powerful ally to develop effective contrast agents for tumors’ medical or photodynamic imaging, to perform direct physical ablation of metastasis, as well as gene therapy. |
format | Online Article Text |
id | pubmed-5371782 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-53717822017-04-10 Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment Sanginario, Alessandro Miccoli, Beatrice Demarchi, Danilo Biosensors (Basel) Review Despite the current progresses of modern medicine, the resistance of malignant tumors to present medical treatments points to the necessity of developing new therapeutic approaches. In recent years, numerous studies have focused their attention on the promising use of nanomaterials, like iron oxide nanowires, zinc oxide or mesoporous silica nanoparticles, for cancer and metastasis treatment with the advantage of operating directly at the bio-molecular scale. Among them, carbon nanotubes emerged as valid candidates not only for drug delivery, but also as a valuable tool in cancer imaging and physical ablation. Nevertheless, deep investigations about carbon nanotubes’ potential bio-compatibility and cytotoxicity limits should be also critically addressed. In the present review, after introducing carbon nanotubes and their promising advantages and drawbacks for fighting cancer, we want to focus on the numerous and different ways in which they can assist to reach this goal. Specifically, we report on how they can be used not only for drug delivery purposes, but also as a powerful ally to develop effective contrast agents for tumors’ medical or photodynamic imaging, to perform direct physical ablation of metastasis, as well as gene therapy. MDPI 2017-02-15 /pmc/articles/PMC5371782/ /pubmed/28212271 http://dx.doi.org/10.3390/bios7010009 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sanginario, Alessandro Miccoli, Beatrice Demarchi, Danilo Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment |
title | Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment |
title_full | Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment |
title_fullStr | Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment |
title_full_unstemmed | Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment |
title_short | Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment |
title_sort | carbon nanotubes as an effective opportunity for cancer diagnosis and treatment |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371782/ https://www.ncbi.nlm.nih.gov/pubmed/28212271 http://dx.doi.org/10.3390/bios7010009 |
work_keys_str_mv | AT sanginarioalessandro carbonnanotubesasaneffectiveopportunityforcancerdiagnosisandtreatment AT miccolibeatrice carbonnanotubesasaneffectiveopportunityforcancerdiagnosisandtreatment AT demarchidanilo carbonnanotubesasaneffectiveopportunityforcancerdiagnosisandtreatment |