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Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment

Despite the current progresses of modern medicine, the resistance of malignant tumors to present medical treatments points to the necessity of developing new therapeutic approaches. In recent years, numerous studies have focused their attention on the promising use of nanomaterials, like iron oxide...

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Detalles Bibliográficos
Autores principales: Sanginario, Alessandro, Miccoli, Beatrice, Demarchi, Danilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371782/
https://www.ncbi.nlm.nih.gov/pubmed/28212271
http://dx.doi.org/10.3390/bios7010009
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author Sanginario, Alessandro
Miccoli, Beatrice
Demarchi, Danilo
author_facet Sanginario, Alessandro
Miccoli, Beatrice
Demarchi, Danilo
author_sort Sanginario, Alessandro
collection PubMed
description Despite the current progresses of modern medicine, the resistance of malignant tumors to present medical treatments points to the necessity of developing new therapeutic approaches. In recent years, numerous studies have focused their attention on the promising use of nanomaterials, like iron oxide nanowires, zinc oxide or mesoporous silica nanoparticles, for cancer and metastasis treatment with the advantage of operating directly at the bio-molecular scale. Among them, carbon nanotubes emerged as valid candidates not only for drug delivery, but also as a valuable tool in cancer imaging and physical ablation. Nevertheless, deep investigations about carbon nanotubes’ potential bio-compatibility and cytotoxicity limits should be also critically addressed. In the present review, after introducing carbon nanotubes and their promising advantages and drawbacks for fighting cancer, we want to focus on the numerous and different ways in which they can assist to reach this goal. Specifically, we report on how they can be used not only for drug delivery purposes, but also as a powerful ally to develop effective contrast agents for tumors’ medical or photodynamic imaging, to perform direct physical ablation of metastasis, as well as gene therapy.
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spelling pubmed-53717822017-04-10 Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment Sanginario, Alessandro Miccoli, Beatrice Demarchi, Danilo Biosensors (Basel) Review Despite the current progresses of modern medicine, the resistance of malignant tumors to present medical treatments points to the necessity of developing new therapeutic approaches. In recent years, numerous studies have focused their attention on the promising use of nanomaterials, like iron oxide nanowires, zinc oxide or mesoporous silica nanoparticles, for cancer and metastasis treatment with the advantage of operating directly at the bio-molecular scale. Among them, carbon nanotubes emerged as valid candidates not only for drug delivery, but also as a valuable tool in cancer imaging and physical ablation. Nevertheless, deep investigations about carbon nanotubes’ potential bio-compatibility and cytotoxicity limits should be also critically addressed. In the present review, after introducing carbon nanotubes and their promising advantages and drawbacks for fighting cancer, we want to focus on the numerous and different ways in which they can assist to reach this goal. Specifically, we report on how they can be used not only for drug delivery purposes, but also as a powerful ally to develop effective contrast agents for tumors’ medical or photodynamic imaging, to perform direct physical ablation of metastasis, as well as gene therapy. MDPI 2017-02-15 /pmc/articles/PMC5371782/ /pubmed/28212271 http://dx.doi.org/10.3390/bios7010009 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sanginario, Alessandro
Miccoli, Beatrice
Demarchi, Danilo
Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment
title Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment
title_full Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment
title_fullStr Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment
title_full_unstemmed Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment
title_short Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment
title_sort carbon nanotubes as an effective opportunity for cancer diagnosis and treatment
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371782/
https://www.ncbi.nlm.nih.gov/pubmed/28212271
http://dx.doi.org/10.3390/bios7010009
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