Altered (neo-) lacto series glycolipid biosynthesis impairs α2-6 sialylation on N-glycoproteins in ovarian cancer cells

The (neo-) lacto series glycosphingolipids (nsGSLs) comprise of glycan epitopes that are present as blood group antigens, act as primary receptors for human pathogens and are also increasingly associated with malignant diseases. Beta-1, 3-N-acetyl-glucosaminyl-transferase 5 (B3GNT5) is suggested as...

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Detalles Bibliográficos
Autores principales: Alam, Shahidul, Anugraham, Merrina, Huang, Yen-Lin, Kohler, Reto S., Hettich, Timm, Winkelbach, Katharina, Grether, Yasmin, López, Mónica Núñez, Khasbiullina, Nailia, Bovin, Nicolai V., Schlotterbeck, Götz, Jacob, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371825/
https://www.ncbi.nlm.nih.gov/pubmed/28358117
http://dx.doi.org/10.1038/srep45367

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