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A Biologically-Based Computational Approach to Drug Repurposing for Anthrax Infection

Developing drugs to treat the toxic effects of lethal toxin (LT) and edema toxin (ET) produced by B. anthracis is of global interest. We utilized a computational approach to score 474 drugs/compounds for their ability to reverse the toxic effects of anthrax toxins. For each toxin or drug/compound, w...

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Detalles Bibliográficos
Autores principales:	Bai, Jane P. F., Sakellaropoulos, Theodore, Alexopoulos, Leonidas G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371854/ https://www.ncbi.nlm.nih.gov/pubmed/28287432 http://dx.doi.org/10.3390/toxins9030099

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