Cargando…

May I Cut in? Gene Editing Approaches in Human Induced Pluripotent Stem Cells

In the decade since Yamanaka and colleagues described methods to reprogram somatic cells into a pluripotent state, human induced pluripotent stem cells (hiPSCs) have demonstrated tremendous promise in numerous disease modeling, drug discovery, and regenerative medicine applications. More recently, t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brookhouser, Nicholas, Raman, Sreedevi, Potts, Christopher, Brafman, David. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371870/ https://www.ncbi.nlm.nih.gov/pubmed/28178187 http://dx.doi.org/10.3390/cells6010005

Ejemplares similares

A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes
por: Knittel, Jacob, et al.
Publicado: (2022)

A Defined and Scalable Peptide-Based Platform for the Generation of Human Pluripotent Stem Cell-Derived Astrocytes
por: Raman, Sreedevi, et al.
Publicado: (2020)

APOE2 mitigates disease-related phenotypes in an isogenic hiPSC-based model of Alzheimer’s disease
por: Brookhouser, Nicholas, et al.
Publicado: (2021)

Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant—Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUI006-A)
por: Brookhouser, Nicholas, et al.
Publicado: (2018)

A transient reporter for editing enrichment (TREE) in human cells
por: Standage-Beier, Kylie, et al.
Publicado: (2020)

A transient reporter for editing enrichment (TREE) in human cells
por: Standage-Beier, Kylie, et al.
Publicado: (2019)

BIG-TREE: Base-Edited Isogenic hPSC Line Generation Using a Transient Reporter for Editing Enrichment
por: Brookhouser, Nicholas, et al.
Publicado: (2020)

A Cell-Based Optimised Approach for Rapid and Efficient Gene Editing of Human Pluripotent Stem Cells
por: Cuevas-Ocaña, Sara, et al.
Publicado: (2023)

Gene Editing in Human Pluripotent Stem Cells: Choosing the Correct Path
por: Singh, Amar M., et al.
Publicado: (2015)

Gene Editing in Pluripotent Stem Cells and Their Derived Organoids
por: Zhou, Hang, et al.
Publicado: (2021)

Progress and Prospects of Gene Editing in Pluripotent Stem Cells
por: Zhang, Zhenwu, et al.
Publicado: (2023)

Gene editing with ‘pencil’ rather than ‘scissors’ in human pluripotent stem cells
por: Park, Ju-Chan, et al.
Publicado: (2023)

 Potential of Gene Editing and Induced Pluripotent Stem Cells (iPSCs) in Treatment of Retinal Diseases 
por: Chuang, Katherine, et al.
Publicado: (2017)

Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration
por: Ovando-Roche, Patrick, et al.
Publicado: (2017)

A Cas9-mediated adenosine transient reporter enables enrichment of ABE-targeted cells
por: Brookhouser, Nicholas, et al.
Publicado: (2020)

Genome editing of human pluripotent stem cells to generate human cellular disease models
por: Musunuru, Kiran
Publicado: (2013)

DICE, an efficient system for iterative genomic editing in human pluripotent stem cells
por: Zhu, Fangfang, et al.
Publicado: (2014)

Base Editing of Human Pluripotent Stem Cells for Modeling Long QT Syndrome
por: Wu, Fujian, et al.
Publicado: (2022)

Protocol for the design, conduct, and evaluation of prime editing in human pluripotent stem cells
por: Wu, Youjun, et al.
Publicado: (2023)

Analysis of SOX2-Expressing Cell Populations Derived from Human Pluripotent Stem Cells
por: Brafman, David A., et al.
Publicado: (2013)

Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells
por: Kumar, Nathan, et al.
Publicado: (2015)

Generation and clinical potential of functional T lymphocytes from gene-edited pluripotent stem cells
por: Guo, Rongqun, et al.
Publicado: (2022)

Simplified Footprint-Free Cas9/CRISPR Editing of Cardiac-Associated Genes in Human Pluripotent Stem Cells
por: Kondrashov, Alexander, et al.
Publicado: (2018)

Application of CRISPR/Cas9 to human-induced pluripotent stem cells: from gene editing to drug discovery
por: De Masi, Claudia, et al.
Publicado: (2020)

CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis
por: Mérien, Antoine, et al.
Publicado: (2021)

Transient inhibition of p53 enhances prime editing and cytosine base-editing efficiencies in human pluripotent stem cells
por: Li, Mu, et al.
Publicado: (2022)

Establishment of Genome-edited Human Pluripotent Stem Cell Lines: From Targeting to Isolation
por: Blair, John D., et al.
Publicado: (2016)

Scarless Genome Editing of Human Pluripotent Stem Cells via Transient Puromycin Selection
por: Steyer, Benjamin, et al.
Publicado: (2018)

Genome Editing and Human Pluripotent Stem Cell Technologies for in vitro Monogenic Diabetes Modeling
por: Dabi, Yosef Tsegaye, et al.
Publicado: (2022)

The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells
por: Huggins, Ian J., et al.
Publicado: (2017)

ET-1 STEM CELL-BASED GENE THERAPY FOR MALIGNANT GLIOMA USING GENOME-EDITED HUMAN INDUCED PLURIPOTENT STEM CELLS
por: Tamura, Ryota, et al.
Publicado: (2022)

Gene-Edited Human-Induced Pluripotent Stem Cell Lines to Elucidate DAND5 Function throughout Cardiac Differentiation
por: Inácio, José M., et al.
Publicado: (2023)

CRISPR-Cas9: a promising tool for gene editing on induced pluripotent stem cells
por: Kim, Eun Ji, et al.
Publicado: (2017)

Using Gene Editing to Establish a Safeguard System for Pluripotent Stem-Cell-Based Therapies
por: Wu, Youjun, et al.
Publicado: (2019)

A Scaled Framework for CRISPR Editing of Human Pluripotent Stem Cells to Study Psychiatric Disease
por: Hazelbaker, Dane Z., et al.
Publicado: (2017)

Base Editing Mediated Generation of Point Mutations Into Human Pluripotent Stem Cells for Modeling Disease
por: Qi, Tao, et al.
Publicado: (2020)

Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards
por: Martin, Renata M., et al.
Publicado: (2020)

FACS-assisted CRISPR-Cas9 genome editing of human induced pluripotent stem cells
por: Caillaud, Amandine, et al.
Publicado: (2022)

A Tet-Inducible CRISPR Platform for High-Fidelity Editing of Human Pluripotent Stem Cells
por: Jurlina, Shawna L., et al.
Publicado: (2022)

Cutting rhythms: intuitive film editing
por: Pearlman, Karen
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_i6fc3uepssdtuk4dgmdc29oqdg