Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases

The burst of reprogramming technology in recent years has revolutionized the field of stem cell biology, offering new opportunities for personalized, regenerative therapies. The direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has provided an invaluable tool to study a...

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Detalles Bibliográficos
Autores principales: Li, Mailin, Cascino, Pasquale, Ummarino, Simone, Di Ruscio, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371872/
https://www.ncbi.nlm.nih.gov/pubmed/28282903
http://dx.doi.org/10.3390/cells6010007
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author Li, Mailin
Cascino, Pasquale
Ummarino, Simone
Di Ruscio, Annalisa
author_facet Li, Mailin
Cascino, Pasquale
Ummarino, Simone
Di Ruscio, Annalisa
author_sort Li, Mailin
collection PubMed
description The burst of reprogramming technology in recent years has revolutionized the field of stem cell biology, offering new opportunities for personalized, regenerative therapies. The direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has provided an invaluable tool to study and model a wide range of human diseases. Here, we review the transforming potential of such a strategy in research and in therapies applicable to the hematology field.
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spelling pubmed-53718722017-04-10 Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases Li, Mailin Cascino, Pasquale Ummarino, Simone Di Ruscio, Annalisa Cells Review The burst of reprogramming technology in recent years has revolutionized the field of stem cell biology, offering new opportunities for personalized, regenerative therapies. The direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) has provided an invaluable tool to study and model a wide range of human diseases. Here, we review the transforming potential of such a strategy in research and in therapies applicable to the hematology field. MDPI 2017-03-08 /pmc/articles/PMC5371872/ /pubmed/28282903 http://dx.doi.org/10.3390/cells6010007 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Li, Mailin
Cascino, Pasquale
Ummarino, Simone
Di Ruscio, Annalisa
Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases
title Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases
title_full Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases
title_fullStr Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases
title_full_unstemmed Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases
title_short Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases
title_sort application of induced pluripotent stem cell technology to the study of hematological diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371872/
https://www.ncbi.nlm.nih.gov/pubmed/28282903
http://dx.doi.org/10.3390/cells6010007
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AT diruscioannalisa applicationofinducedpluripotentstemcelltechnologytothestudyofhematologicaldiseases

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