NMDA receptor antagonism with novel indolyl, 2-(1,1-Dimethyl-1,3-dihydro-benzo[e]indol-2-ylidene)-malonaldehyde, reduces seizures duration in a rat model of epilepsy

N-methyl-D-aspartate receptors (NMDAR) play a central role in epileptogensis and NMDAR antagonists have been shown to have antiepileptic effects in animals and humans. Despite significant progress in the development of antiepileptic therapies over the previous 3 decades, a need still exists for nove...

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Detalles Bibliográficos
Autores principales: Rothan, Hussin A., Amini, Elham, Faraj, Fadihl L., Golpich, Mojtaba, Teoh, Teow Chong, Gholami, Khadijeh, Yusof, Rohana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371989/
https://www.ncbi.nlm.nih.gov/pubmed/28358047
http://dx.doi.org/10.1038/srep45540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371989/
https://www.ncbi.nlm.nih.gov/pubmed/28358047
http://dx.doi.org/10.1038/srep45540

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