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Metaphase Spindle Assembly

A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells.

Detalles Bibliográficos
Autor principal: Kapoor, Tarun M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372001/
https://www.ncbi.nlm.nih.gov/pubmed/28165376
http://dx.doi.org/10.3390/biology6010008
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author Kapoor, Tarun M.
author_facet Kapoor, Tarun M.
author_sort Kapoor, Tarun M.
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description A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells.
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spelling pubmed-53720012017-04-10 Metaphase Spindle Assembly Kapoor, Tarun M. Biology (Basel) Review A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells. MDPI 2017-02-03 /pmc/articles/PMC5372001/ /pubmed/28165376 http://dx.doi.org/10.3390/biology6010008 Text en © 2017 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kapoor, Tarun M.
Metaphase Spindle Assembly
title Metaphase Spindle Assembly
title_full Metaphase Spindle Assembly
title_fullStr Metaphase Spindle Assembly
title_full_unstemmed Metaphase Spindle Assembly
title_short Metaphase Spindle Assembly
title_sort metaphase spindle assembly
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372001/
https://www.ncbi.nlm.nih.gov/pubmed/28165376
http://dx.doi.org/10.3390/biology6010008
work_keys_str_mv AT kapoortarunm metaphasespindleassembly