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Metaphase Spindle Assembly
A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372001/ https://www.ncbi.nlm.nih.gov/pubmed/28165376 http://dx.doi.org/10.3390/biology6010008 |
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author | Kapoor, Tarun M. |
author_facet | Kapoor, Tarun M. |
author_sort | Kapoor, Tarun M. |
collection | PubMed |
description | A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells. |
format | Online Article Text |
id | pubmed-5372001 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-53720012017-04-10 Metaphase Spindle Assembly Kapoor, Tarun M. Biology (Basel) Review A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells. MDPI 2017-02-03 /pmc/articles/PMC5372001/ /pubmed/28165376 http://dx.doi.org/10.3390/biology6010008 Text en © 2017 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kapoor, Tarun M. Metaphase Spindle Assembly |
title | Metaphase Spindle Assembly |
title_full | Metaphase Spindle Assembly |
title_fullStr | Metaphase Spindle Assembly |
title_full_unstemmed | Metaphase Spindle Assembly |
title_short | Metaphase Spindle Assembly |
title_sort | metaphase spindle assembly |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372001/ https://www.ncbi.nlm.nih.gov/pubmed/28165376 http://dx.doi.org/10.3390/biology6010008 |
work_keys_str_mv | AT kapoortarunm metaphasespindleassembly |