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Biological rationale and potential clinical use of gabapentin and pregabalin in bipolar disorder, insomnia and anxiety: protocol for a systematic review and meta-analysis
INTRODUCTION: Gabapentin has been extensively prescribed off-label for psychiatric indications, with little established evidence of efficacy. Gabapentin and pregabalin, a very similar drug with the same mechanism of action, bind to a subunit of voltage-dependent calcium channels which are implicated...
Autores principales: | Houghton, Kerensa T, Forrest, Alexandra, Awad, Amine, Atkinson, Lauren Z, Stockton, Sarah, Harrison, Paul J, Geddes, John R, Cipriani, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372050/ https://www.ncbi.nlm.nih.gov/pubmed/28348186 http://dx.doi.org/10.1136/bmjopen-2016-013433 |
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