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MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium

Leukocyte adhesion to brain endothelial cells, the blood-brain barrier main component, is a critical step in the pathogenesis of neuroinflammatory diseases such as multiple sclerosis (MS). Leukocyte adhesion is mediated mainly by selectins, cell adhesion molecules and chemokines induced by pro-infla...

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Detalles Bibliográficos
Autores principales: Cerutti, Camilla, Edwards, Laura J., de Vries, Helga E., Sharrack, Basil, Male, David K., Romero, Ignacio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372244/
https://www.ncbi.nlm.nih.gov/pubmed/28358058
http://dx.doi.org/10.1038/srep45284