Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome

BACKGROUND: Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different molecular levels in order to identify integrated subtypes. METHODS: Tumor tissue from 425 patients with primary breast cancer from the Os...

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Detalles Bibliográficos
Autores principales: Aure, Miriam Ragle, Vitelli, Valeria, Jernström, Sandra, Kumar, Surendra, Krohn, Marit, Due, Eldri U., Haukaas, Tonje Husby, Leivonen, Suvi-Katri, Vollan, Hans Kristian Moen, Lüders, Torben, Rødland, Einar, Vaske, Charles J., Zhao, Wei, Møller, Elen K., Nord, Silje, Giskeødegård, Guro F., Bathen, Tone Frost, Caldas, Carlos, Tramm, Trine, Alsner, Jan, Overgaard, Jens, Geisler, Jürgen, Bukholm, Ida R. K., Naume, Bjørn, Schlichting, Ellen, Sauer, Torill, Mills, Gordon B., Kåresen, Rolf, Mælandsmo, Gunhild M., Lingjærde, Ole Christian, Frigessi, Arnoldo, Kristensen, Vessela N., Børresen-Dale, Anne-Lise, Sahlberg, Kristine K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372339/
https://www.ncbi.nlm.nih.gov/pubmed/28356166
http://dx.doi.org/10.1186/s13058-017-0812-y

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